Related Experiment Video
Updated: May 1, 2026

Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
Published on: August 22, 2025
Downbeat nystagmus elicited by eyelid closure
João Lemos1, Daniela Pereira, Margarida Amorim
1Departments of Neurology (JL, BS, LC), Neuroradiology (DP), and Otorhinolaryngology (MA, AP), Coimbra University Hospital Center, Coimbra, Portugal.
Abstract:
We describe a patient with downbeat nystagmus (DBN) evoked only by eye closure. Brain and spinal cord magnetic resonance imaging revealed a T2 paramedian lesion in the left lower basis pontis and other white matter lesions consistent with multiple sclerosis. One potential mechanism for DBN in this case involves transverse ephaptic spread of excitation from areas that subserve coordinated lid closure to the decussating ventral tegmental tract.
More Related Videos
06:12Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram
Published on: March 13, 2018
09:28Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice
Published on: June 23, 2023
Related Concept Videos
Accessory Structures of the Eye
Muscles of the Eye
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...