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Fluorescence Lifetime Macro Imager for Biomedical Applications
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A turn-on fluorescent Fe(3+) sensor derived from an anthracene-bearing bisdiene macrocycle and its intracellular
Lin Qiu1, Chengcheng Zhu, Huachao Chen
1State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. heweij69@nju.edu.cn zguo@nju.edu.cn.
Chemical Communications (Cambridge, England)
|March 27, 2014
Abstract:
Integrating N(2)-hydroxyethyldiethylenetriamine with anthracene gives a [2+2] macrocycle fluorescent sensor. This sensor displays an instant/reversible turn-on response specific to Fe(3+), which allows facile visualization of the Fe(3+)/Fe(2+) transition and intracellular Fe(3+) imaging.
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