Related Experiment Video
Updated: May 1, 2026
Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
[Clinical efficacy of tissue adhesive on intractable bleeding during endoscopic submucosal dissection]
Lili Ma1, Jingjing Lian, Pinghong Zhou
1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China. chen.shiyao@zs-hospital.sh.cn.
Objective:
To investigate the efficacy of tissue adhesive on intractable bleeding during endoscopic submucosal dissection(ESD) and delayed bleeding.
Methods:
A total of 9874 patients with gastrointestinal mucosal or submucosal tumors underwent ESD in our center from September 2006 to August 2013 and intractable bleeding occurred during ESD in 5 cases. Under the condition of no effective hemostasis methods, the tissue adhesive injection or spray were used to stop the bleeding. The efficacy and safety were evaluated.
Results:
All the 5 cases were successfully managed by the hemostasis method with tissue adhesive without any adverse event. In follow-up of two months after operation, wound healing and scar formation were observed under endoscopy.
Conclusion:
Tissue adhesive is safe, effective and fast for intractable bleeding during ESD and delayed bleeding.
