Related Experiment Video
Updated: May 1, 2026

A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
Published on: August 7, 2020
Nested stromal-epithelial tumour of the liver: An unusual liver entity
Fabio Procopio1, Luca Di Tommaso1, Silvia Armenia1
1Fabio Procopio, Guido Torzilli, Department of Hepatobiliary Surgery, University of Milan, Humanitas Research Hospital, Rozzano, 20089 Milan, Italy.
Abstract:
Nested stromal-epithelial tumours (NSETs) of the liver have been reported to be extremely unusual primary hepatic neoplasms. To date, few cases have been described in the literature. NSETs have been defined as non-hepatocytic and non-biliary tumours of the liver consisting of nests of epithelial and spindled cells, myofibroblastic stroma and variable intralesional calcification and ossification. Here, we report a case of a young female who underwent liver resection for a large hepatic lesion that proved to be a calcifying NSET on pathological examination. Details about the clinical and histopathological features of the tumour are reported.

