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Updated: May 1, 2026

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
Published on: September 9, 2020
Surgical treatment of hypertrophic cardiomyopathy
Sameh M Said1, Hartzell V Schaff1
1Division of Cardiovascular Surgery, College of Medicine, Mayo Clinic, Rochester, Minnesota.
Insights
Hypertrophic cardiomyopathy (HCM) is a heart muscle disease causing unexplained left ventricular hypertrophy. Surgical septal myectomy is the preferred treatment for HCM when medical options fail or are not tolerated.
Area of Science:
- Cardiology
- Genetics
- Internal Medicine
Background:
- Hypertrophic cardiomyopathy (HCM) is a primary myocardial disease.
- Characterized by unexplained left ventricular hypertrophy without other causes.
- Key features include systolic anterior motion of the mitral valve, leading to outflow tract obstruction and regurgitation.
Purpose of the Study:
- To review the available treatment options for Hypertrophic Cardiomyopathy (HCM).
- To provide an overview of medical and surgical interventions for HCM management.
Main Methods:
- Literature review of current treatment strategies for HCM.
- Summary of established and emerging therapies.
Main Results:
- Medical management is the initial approach for HCM.
- Surgical septal myectomy is the preferred intervention when medical treatment is insufficient or not tolerated.
- Various degrees of mitral valve regurgitation can occur.
Conclusions:
- HCM requires careful management due to potential complications.
- Surgical septal myectomy offers a definitive treatment option for obstructive HCM.
- Comprehensive understanding of treatment options is crucial for patient care.
Abstract:
Hypertrophic cardiomyopathy (HCM) is a unique primary myocardial disease characterized by unexplained left ventricular hypertrophy in absence of another etiology. One of the key features is the presence of systolic anterior motion of the anterior leaflet of the mitral valve which causes left ventricular outflow tract obstruction with various degrees of mitral valve regurgitation. Surgical septal myectomy is the preferred treatment of choice if medical treatment is unsuccessful or intolerable. We summarize in this review the available treatment options for HCM.
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