Thyroidal abscesses in third and fourth branchial anomalies: not only a paediatric diagnosis
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Updated: May 1, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Schelto Kruijff1, Mark S Sywak1, Stan B Sidhu1
1Endocrine Surgical Unit, The University of Sydney, Sydney, New South Wales, Australia.
Insights
Thyroid abscesses and acute suppurative thyroiditis, often linked to branchial cleft anomalies, are not exclusive to children. This condition can affect adults, emphasizing the need for prompt diagnosis and treatment in all age groups.
Area of Science:
- Otolaryngology
- Endocrinology
- Pediatric Surgery
Background:
- Acute suppurative thyroiditis and recurrent abscesses are typically associated with third and fourth branchial anomalies in children.
- However, these thyroid abscesses can also manifest in adults, often stemming from branchial cleft anomalies.
- Delayed recognition and treatment of neck abscesses can lead to severe, life-threatening complications.
Purpose of the Study:
- To investigate the occurrence and management of thyroid abscesses in relation to branchial cleft anomalies across different age groups.
- To highlight that thyroid abscesses are not solely a pediatric diagnosis.
Main Methods:
- A retrospective case series was conducted over a 12-month period (January-December 2012).
- The study included patients with thyroid abscesses and branchial cleft anomalies from both adult and pediatric centers.
- Data collected included demographics, clinical presentation, imaging, surgical management, histology, and outcomes.
Main Results:
- Five patients were identified: one child (9 years) and four adults (20-41 years).
- All patients presented with third or fourth left branchial cleft anomalies, leading to suppurative thyroiditis and left-sided thyroid abscesses.
- Management varied, including abscess drainage, primary thyroid lobectomy, or delayed lobectomy after drainage.
Conclusions:
- Acute suppurative thyroiditis and thyroid abscesses can occur at any age, not just in children.
- Thyroid abscesses in both children and adults are almost invariably linked to underlying branchial cleft anomalies.
Introduction:
Acute suppurative thyroiditis and recurrent abscess formation due to third and fourth branchial anomalies typically present in children. However, thyroid abscesses in branchial anomalies may occur in adulthood as well. Failure to recognize and delayed drainage of a neck abscess may lead to a fulminant life-threatening outcome.
Methods:
This is a retrospective case series. The study group comprised all patients presenting over a 12-month period from January to December 2012 with thyroid abscesses and a branchial cleft anomaly in two centres, one adult and the other paediatric. Patient demographics, clinical presentation, imaging, surgical management, definitive histology and outcomes were documented.
Results:
Five patients were identified with a history of thyroid abscesses. Only one was a child (aged 9 years) with the other four being adults (aged 20, 34, 37 and 41 years). All patients had third or fourth left branchial cleft anomalies, presenting as suppurative thyroiditis with a left-sided thyroid abscess. Management options ranged from abscess drainage on initial presentation, primary thyroid lobectomy or delayed thyroid lobectomy following abscess drainage.
Conclusion:
Acute suppurative thyroidits and thyroid abscesses is not just a paediatric diagnosis but may present at any age. In both children and adults, a thyroid abscess almost always arises from branchial cleft anomalies.
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