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Retracted: Methotrexate in the treatment of symptomatic knee osteoarthritis: randomised placebo-controlled trial

A Abou-Raya1,2, S Abou-Raya2,3, T Khadrawe4

  • 1Rheumatology Department, University of Alexandria, Alexandria, Egypt.

Annals of the Rheumatic Diseases
|March 29, 2014
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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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