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Updated: May 1, 2026

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Comparison between particulate matter and ultrafine particle emission by electronic and normal cigarettes in
Aims:
Electronic cigarettes may be safer than conventional cigarettes as they generate less indoor pollution in terms of particulate matter (PM); however, recent findings in experimental conditions demonstrated that secondhand exposure to PM may be expected from e-cigarette smoking. The aim of the present study was to investigate the emission of PM generated by e-cigarettes and normal cigarettes under real-life conditions.
Methods:
Real-time measurement and comparison of PM and ultrafine particles (UFP) generated by electronic cigarettes with and without nicotine and by normal cigarettes in a 50 m3 office of an Italian comprehensive cancer center was performed. PM mass as PM1, PM2.5, PM7, PM10, total suspended particles (TSP) in μg/m³ and UFP in number of particles per cubic centimeter from 10 to 1,000 nanometers were measured. Outdoor concentrations were measured contemporaneously to compensate for urban background changes.
Results:
Regardless of their nicotine content, e-cigarettes generated lower PM levels than conventional cigarettes. Notably, nicotine-enriched e-cigarettes produced lower PM levels than their nicotine-free counterparts.
Conclusion:
E-cigarettes appear to generate less indoor pollution than normal cigarettes and may therefore be safer. Further studies are required to investigate the long-term health-related effects of secondhand e-cigarette exposure.
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