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Study of risk factors associated with peripheral arteriopathy in Japanese-Brazilians from Bauru (SP)

Luciana Garofolo1, Sandra Roberta G Ferreira2, Fausto Miranda Junior3

  • 1Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil.

Arquivos Brasileiros De Cardiologia
|March 29, 2014
PubMed

Insights

Peripheral arterial disease (PAD) affects 21.1% of Japanese-Brazilians, linked to smoking and hypertension. This highlights the need for targeted cardiovascular disease prevention in at-risk populations.

Area of Science:

  • Cardiovascular Medicine
  • Epidemiology
  • Vascular Health

Background:

  • Cardiovascular diseases are a leading cause of death globally, with atherosclerosis as a primary driver.
  • Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis, impacting coronary health.
  • Understanding PAD prevalence and risk factors is crucial for managing complications and healthcare costs.

Purpose of the Study:

  • To determine the prevalence of PAD in a Japanese-Brazilian population in Bauru, São Paulo.
  • To investigate the association between PAD and metabolic risk biomarkers in this demographic.
  • To assess the impact of high metabolic disorder prevalence (hypertension, diabetes, hypercholesterolemia) on PAD.

Main Methods:

  • A cross-sectional population study involving 1,038 Japanese-Brazilians aged 30 and above.
  • Evaluations included physical examinations, anthropometric measurements, laboratory tests, and ankle-brachial index (ABI) assessment.
  • PAD was diagnosed with an ABI ≤ 0.90; Poisson regression analyzed associations with risk factors.

Main Results:

  • The prevalence of PAD was 21.1% in the study population, with no significant gender difference.
  • PAD showed a significant association with current smoking (Prevalence Ratio [PR] 2.16) and hypertension (PR 1.56).
  • Other classical risk factors were not independently associated with PAD in this cohort.

Conclusions:

  • The PAD prevalence in Japanese-Brazilians is comparable to other populations with high cardiometabolic risk.
  • Smoking and hypertension are independently associated with PAD in this group.
  • The specific metabolic profile of this population may influence the observed associations with PAD risk factors.
Abstract

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