Related Experiment Video

Updated: May 1, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

11.6K

Prescriber perceptions of a pediatric antimicrobial stewardship program

Dustin D Flannery1, Sanjeev Swami2, Shannon Chan2

  • 1Alfred I duPont Hospital for Children, Wilmington, DE, USA vtdus10@gmail.com.

Clinical Pediatrics
|March 29, 2014
PubMed

Insights

Antimicrobial stewardship programs (ASPs) improve antimicrobial use and reduce resistance. A survey at a pediatric hospital found ASP interventions were perceived as useful and well-received by prescribers, positively influencing prescribing behaviors.

Area of Science:

  • Infectious Diseases
  • Hospital Pharmacy
  • Public Health

Background:

  • Antimicrobial resistance is a growing global health threat.
  • Antimicrobial stewardship programs (ASPs) are crucial for optimizing antimicrobial use in healthcare settings.
  • Effective ASPs can mitigate the development of antimicrobial resistance.

Purpose of the Study:

  • To evaluate the perceived effectiveness of antimicrobial stewardship program (ASP) interventions on healthcare providers' prescribing behavior.
  • To assess provider reception of ASP interventions at a pediatric tertiary care center.

Main Methods:

  • An online survey was administered to hospital-based providers.
  • The survey used a Likert scale response format to gauge perceptions of ASP interventions.
  • Data were collected from providers at a pediatric tertiary care center that implemented an ASP in 2004.

Main Results:

  • The hospital's ASP was perceived as useful in enhancing antimicrobial prescribing practices.
  • Prescribers generally received the ASP interventions favorably.
  • The study indicated positive impacts of ASP interventions on prescribing behaviors.

Conclusions:

  • Antimicrobial stewardship programs are perceived positively by healthcare providers.
  • ASP interventions can effectively influence and improve antimicrobial prescribing behavior.
  • Hospitals can expect positive outcomes when implementing ASPs to combat antimicrobial resistance.

Keywords:
antimicrobial resistanceantimicrobial stewardship programpediatricssurvey

More Related Videos

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

22.2K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

29.0K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
408
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
967
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
410
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
116
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
554
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
1.0K