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Changes in choroidal thickness after trabeculectomy in primary angle closure glaucoma.

Shida Chen1, Wei Wang, Xinbo Gao

  • 1Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, People's Republic of China.

Investigative Ophthalmology & Visual Science
|March 29, 2014
PubMed
Summary

Choroidal thickness (CT) increased after trabeculectomy in primary angle closure glaucoma (PACG) patients. This short-term increase in CT was not linked to reduced intraocular pressure (IOP) or axial length changes.

Keywords:
axial lengthchoroidal thicknessintraocular pressuretrabeculectomy

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Choroidal Imaging

Background:

  • Primary angle closure glaucoma (PACG) is a leading cause of irreversible blindness.
  • Trabeculectomy is a surgical procedure to lower intraocular pressure (IOP) in advanced glaucoma.
  • Understanding changes in ocular structures post-surgery is crucial for patient management.

Purpose of the Study:

  • To evaluate short-term changes in choroidal thickness (CT) after trabeculectomy in patients with advanced PACG.
  • To explore the relationship between CT changes and variations in IOP and axial length post-surgery.

Main Methods:

  • Enhanced depth imaging optical coherence tomography (EDI-OCT) was used to measure CT.
  • CT was measured in 23 eyes with PACG before and 7 days after trabeculectomy.
  • Correlations between CT changes, IOP, and axial length were analyzed.

Main Results:

  • Choroidal thickness (CT) significantly increased at most macular locations 7 days after trabeculectomy.
  • Mean CT under the fovea increased from 282.3 μm to 311.6 μm.
  • Mean IOP decreased significantly from 25.9 mm Hg to 11.8 mm Hg, correlating with shortened axial length, but CT changes were not correlated with IOP or axial length.

Conclusions:

  • Trabeculectomy leads to a short-term increase in choroidal thickness (CT) in PACG patients.
  • This CT increase was not associated with the observed decrease in intraocular pressure (IOP) or axial length.
  • The clinical significance of post-trabeculectomy CT changes requires further investigation.