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Updated: May 1, 2026

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
Published on: December 27, 2013
Botulinum toxin: The Midas touch
P S Shilpa1, Rachna Kaul1, Nishat Sultana1
1Department of Oral Medicine and Radiology, Vydehi Institute of Dental Sciences, No. 82, EPIP Area, White Field, Bangalore, India.
Abstract:
Botulinum Toxin (BT) is a natural molecule produced during growth and autolysis of bacterium called Clostridium botulinum. Use of BT for cosmetic purposes has gained popularity over past two decades, and recently, other therapeutic uses of BT has been extensively studied. BT is considered as a minimally invasive agent that can be used in the treatment of various orofacial disorders and improving the quality of life in such patients. The objective of this article is to review the nature, mechanism of action of BT, and its application in various head and neck diseases.
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