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HEMA-particles phagocytosis of rat neutrophils
1Laboratory of Haematology, Research Institute for Pharmacy and Biochemistry, Pardubice, CSSR.
Abstract:
A micromethod for testing of phagocytosis employing synthetic hydrophilic HEMA particles seems to be suitable for an examination of rat neutrophils. The normal phagocytic activity was 53.7 +/- 1.4%, phagocytic index 8.2 +/- 0.7, and the number of phagocytosing neutrophils was found to be 74 +/- 5.10(6)/l. Using HEMA particles, an experimentally induced depression of rat neutrophil phagocytosis after cyclophosphamide or benflurone was well detected and quantified.