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Related Concept Videos

Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

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Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
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Related Experiment Video

Updated: May 1, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
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Indirect decompression for a prior severe C1-2 dislocation causing progressive quadriparesis.

Kyeong Hwan Kim1, Dong Bong Lee, Ho-Joong Kim

  • 1Spine Center and Department of Orthopaedic Surgery, Hyundae General Hospital, Namyangju, Korea;

Journal of Neurosurgery. Spine
|April 1, 2014
PubMed
Summary

This study demonstrates that posterior C1-2 segmental screw fixation can effectively treat severe childhood C1-2 dislocations causing quadriparesis. The minimally invasive approach achieved satisfactory decompression and bone union, leading to good neurological recovery.

Keywords:
cervicaldislocationindirect decompressionquadriparesis

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Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Spinal Surgery

Background:

  • Severe C1-2 dislocations in childhood often require combined anterior-posterior surgery due to challenges in reduction and decompression.
  • Delayed treatment of such injuries can lead to progressive neurological deficits like quadriparesis.

Observation:

  • A 14-year-old male with a history of C1-2 fracture-dislocation at age 3, treated non-operatively with a Minerva cast, presented with progressive quadriparesis.
  • The patient underwent posterior C1-2 segmental screw fixation as the sole surgical intervention.

Findings:

  • The posterior C1-2 segmental screw fixation successfully achieved adequate neural decompression without requiring direct bone decompression or additional surgical procedures.
  • Complete bone union was confirmed post-operatively.
  • The patient experienced satisfactory neurological recovery at the 5-year follow-up.

Implications:

  • Posterior C1-2 segmental screw fixation represents a viable, less invasive alternative for managing severe, late-presenting C1-2 dislocations in pediatric patients.
  • This technique may offer a simpler surgical solution with good long-term outcomes for spinal cord decompression and stabilization.
  • Further research could explore the long-term efficacy and potential complications of this approach in a larger cohort.