Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...

Acute Pancreatitis II: Clinical Manifestations and Management

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Alcohol Use is Associated with Unplanned Hospital Events in Trauma Patients.

The Journal of surgical research·2026

Same author

Incidence of pulmonary complications in rib fracture patients after surgical stabilization of rib fractures compared to RibScore prognostication.

Injury·2026

Same author

Effect of anticoagulation on isolated traumatic brain injury mortality using TQIP database: a propensity score analysis stratified by head injury severity.

Trauma surgery & acute care open·2025

Same author

The Atypical Presentation and Delayed Timing of Anastomotic Leak in Patients Who Undergo Cytoreducation and Hyperthermic Intraperitoneal Chemotherapy.

The Journal of surgical research·2025

Same author

Distant Tumor Response in the Pelvis After Histotripsy of a Metastatic Sarcoma of the Liver in a Patient With Differentiated Liposarcoma.

The American surgeon·2025

Same author

Use of Histotripsy to Rapidly Relieve Biliary Obstruction in a Patient With Recurrent Hilar Cholangiocarcinoma.

The American surgeon·2025

Same journal

Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026

Same journal

Beyond the Scalpel's Reach.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Society.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Hospitals.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions for Providers.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Patients Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 1, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Gallstone pancreatitis: a review.

Daniel Cucher¹, Narong Kulvatunyou², Donald J Green²

¹Department of Surgery, College of Medicine, University of Arizona, PO Box 245005, Tucson, AZ 85724, USA.

The Surgical Clinics of North America

|April 1, 2014

Summary

This summary is machine-generated.

Gallstone pancreatitis is common, usually mild, and treated with gallbladder removal (cholecystectomy). Severe cases require meticulous management to reduce mortality risks.

Keywords:

Biliary acute pancreatitis Diagnosis Early cholecystectomy Gallstone pancreatitis Management

More Related Videos

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Published on: April 1, 2022

Related Experiment Videos

Last Updated: May 1, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Published on: April 1, 2022

Area of Science:

Gastroenterology
Surgical Management

Background:

Gallstone disease is the leading cause of acute pancreatitis in Western countries.
Most gallstone pancreatitis cases are mild and self-limiting.

Purpose of the Study:

To review the disease process, diagnosis, and management of gallstone pancreatitis.
To focus on surgical management, including timing and intervention choices.

Main Methods:

Review of existing literature on gallstone pancreatitis.
Analysis of diagnostic criteria and severity stratification.
Discussion of surgical interventions and their timing.

Main Results:

Gallstone pancreatitis is the most common cause of acute pancreatitis.
Severe cases (20%) have significant mortality.
Cholecystectomy prevents recurrence in mild cases.

Conclusions:

Understanding gallstone pancreatitis is crucial for effective patient care.
Meticulous management and appropriate surgical intervention are key, especially in severe cases.