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Updated: May 1, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Convenient and selective "off-on" detection nitric oxide in solution and thin film with quinoline based fluorescence
Miao Yu1, Wei Wang2, Ning Zhang1
1Department of Chemistry and Chemical Engineering, Huanghuai University, Zhumadian 463000, China.
Abstract:
Quinoline based fluorescence sensor (1) was synthesized and characterized with mass spectra (MS), ((1))H nuclear magnetic resonance (((1))H NMR) spectrometer, elemental analyses, and infrared (IR) spectra. Following fluorescence experiments demonstrate 1 can coordinate with copper ions, and lead to fluorescence completely quenched. The 1-copper complex was used as a "turn-on" fluorescence biosensor to convenient and highly effective detect nitric oxide (NO) over other radicals in solution and PCL-based thin film. The finding would enable the quinoline based fluorescence probe to be an "off-on" convenient NO fluorescence probe.
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