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Updated: Jan 18, 2026

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
Published on: July 14, 2023
[Bone and Stem Cells. Mesenchymal stem cells and bone regeneration]
Motohiro Komaki1, Kengo Iwasaki, Ikuo Morita
1Tokyo Medical and Dental University Graduate School of Medeical and Dentai Science, Department of Nanomedicine (DNP) , Japan.
Abstract:
Mesenchymal stem cells (MSCs) have multi-differentiation potency, and enhance wound healing in various kinds of disease. Recently MSC not only differentiate into tissue-forming cells, but also secrete various kinds of cytokines and chemokines that are anti-apoptotic, immunomodulatory, angiogenic, and the cell-mobilizing to influence extracellular environment. In addition, we show that MSC has a novel intercellular communication mechanism. It hopes to suggest ways to make safer and reliable usage of MSC in bone regeneration.
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