Reducing the burden of postoperative ileus: evaluating and implementing an evidence-based strategy
Jeffrey F Barletta1, Anthony J Senagore
1Department of Pharmacy Practice, College of Pharmacy-Glendale, Midwestern University, 19555 N 59th Avenue, Glendale, AZ, 85308, USA, jbarle@midwestern.edu.
Postoperative ileus (POI) significantly burdens healthcare. This review details evidence-based strategies for preventing and treating POI, focusing on implementation for improved patient outcomes and reduced hospital stay.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Health Services Research
Background:
- Postoperative ileus (POI) presents a substantial clinical and economic challenge.
- Despite advancements, the incidence of POI remains high.
- This review addresses interventions to mitigate POI's impact.
Purpose of the Study:
- To review interventions for preventing and treating postoperative ileus.
- To present a step-by-step implementation process for evidence-based strategies.
- To highlight factors influencing gastrointestinal recovery.
Main Methods:
- A comprehensive literature search was conducted using Medline/PubMed.
- Relevant articles on postoperative ileus were identified and reviewed.
- Bibliographies of retrieved articles were screened for additional sources.
Main Results:
- Gastrointestinal recovery is influenced by management, drug, and surgery-related factors.
- Several strategies can improve gastrointestinal recovery, but few reduce hospital stay.
- A structured approach considering preoperative, intraoperative, and postoperative phases is presented.
Conclusions:
- Postoperative ileus incurs significant clinical and economic costs.
- Multidisciplinary teams and multimodal protocols are recommended for POI management.
- Continuous quality assurance is vital for assessing local outcomes.
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