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Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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iPS Cell Differentiation01:22

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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Stem Cell Therapy for Tissue Regeneration01:21

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Induced Pluripotent Stem Cells01:13

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
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Embryonic Stem Cells00:58

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Updated: May 1, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
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Stem cell research: applicability in dentistry.

Shivani Mathur, Rahul Chopra, I K Pandit

    The International Journal of Oral & Maxillofacial Implants
    |April 1, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Stem cell research offers hope for tissue regeneration. Dental stem cells can potentially repair and regenerate damaged teeth and periodontal structures, addressing a significant clinical challenge.

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    Area of Science:

    • Regenerative Medicine
    • Dental Research
    • Biomaterials

    Background:

    • Tissue and organ regeneration remains a significant challenge despite medical advances.
    • Dental professionals face difficulties in regenerating damaged periodontal tissue, bone, pulp, and dentin.

    Purpose of the Study:

    • To explore the potential of stem cells in regenerating dental and periodontal structures.
    • To highlight the role of stem cells in addressing limitations in current dental treatments.

    Main Methods:

    • Harvesting stem cells from dental pulp, periodontal ligament, and alveolar bone marrow.
    • Expanding and embedding these stem cells in suitable scaffolds for transplantation.
    • Utilizing these cells for the regeneration of bone and tooth structures.

    Main Results:

    • Dental stem cells demonstrate potential for regenerating dentin, periodontal ligament, and cementum.
    • These cells can be used to restore bone defects in the jaw.

    Conclusions:

    • Stem cell therapy holds significant promise for dental regeneration and treating periodontal diseases.
    • Careful consideration of scaffolds, cell sources, culturing, and surgical procedures is crucial for successful clinical application.