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Updated: Aug 11, 2026
09:52
Imaging and Analysis of Neurofilament Transport in Excised Mouse Tibial Nerve
Published on: August 31, 2020
A model for slow axonal transport and its application to neurofilamentous neuropathies
Cell Motility and the Cytoskeleton
|January 1, 1989
Abstract:
A model for slow axonal transport is developed in which the essential features are reversible binding of cytoskeletal elements and of soluble cytosolic proteins to each other and to motile elements such as actin microfilaments. Computer simulation of the equations of the model demonstrate that the model can account for many of the features of the SCa and SCb waves observed in pulse experiments. The model also provides a unified explanation for the increase and decrease of neurofilament transport rates observed in various toxicant-induced neuropathies.
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