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Updated: May 1, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Alcohol amination with ammonia catalyzed by an acridine-based ruthenium pincer complex: a mechanistic study
Xuan Ye1, Philipp N Plessow, Marion K Brinks
1Catalysis Research Laboratory (CaRLa) , Im Neuenheimer Feld 584, D-69120 Heidelberg, Germany.
Abstract:
The mechanistic course of the amination of alcohols with ammonia catalyzed by a structurally modified congener of Milstein's well-defined acridine-based PNP-pincer Ru complex has been investigated both experimentally and by DFT calculations. Several key Ru intermediates have been isolated and characterized. The detailed analysis of a series of possible catalytic pathways (e.g., with and without metal-ligand cooperation, inner- and outer-sphere mechanisms) leads us to conclude that the most favorable pathway for this catalyst does not require metal-ligand cooperation.
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