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Updated: May 1, 2026

Using Learning Outcome Measures to assess Doctoral Nursing Education
Published on: June 21, 2010
[GRADE: Methodology for formulating and grading recommendations in clinical practice]
Andrea Juliana Sanabria1, David Rigau1, Rafael Rotaeche2
1Centro Cochrane Iberoamericano, Instituto de Investigación Biomédica (IIB-Sant Pau), Barcelona, España.
Abstract:
Clinical practice guidelines (CPG) provide recommendations on the benefits and harms of different healthcare interventions. Proper CPG development and implementation can potentially reduce variability in clinical practice while improving its quality and safety. The GRADE system is used to assess the quality of evidence and to grade the strength of recommendations in the context of the development of CPGs, systematic reviews or health technology assessments. The aim of this article is to describe the main characteristics of the GRADE system through relevant examples in the context of primary care.
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