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Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells

Chen Yan1, Li Huang2, Hong-Chun Liu3

  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China; University of Chinese Academy of Sciences, Beijing 100039, PR China; The Key Laboratory of Chemistry for Natural Product of Guizhou Province, Chinese Academy of Science, Beijing 100101, PR China.

Bioorganic & Medicinal Chemistry Letters
|April 2, 2014
PubMed

Keywords:
ApoptosisBax(−/−)/Bak(−/−) cellsCytotoxicitySpiramine derivativeα,β-Unsaturated ketone

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