Related Experiment Video
Updated: May 1, 2026

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses
Published on: November 4, 2025
Skin manifestations of arthropod-borne infection in Latin America
Adrián Bolivar-Mejia1, Camila Alarcón-Olave, Alfonso J Rodriguez-Morales
1aFaculty of Health, Universidad Industrial de Santander bFaculty of Medicine, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia cFaculty of Health Sciences, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia dWorking Group on Zoonoses, International Society for Chemotherapy, Aberdeen, UK.
Purpose Of Review:
Arthropods are a significant cause of human skin lesions and infections, especially in Latin America. This review summarizes recent articles on the cutaneous manifestations of arthropod-borne diseases, with an emphasis on those diseases causing direct skin damage but also considering those systemic diseases with cutaneous manifestations.
Recent Findings:
Studies have shown a variety and increase of cutaneous manifestations caused by arthropod-borne infections, including petechiae, purpura, ulcers, nodules, atrophic, miliary and hyperpigmented lesions. Although unspecific, when considering other features they become a useful tool in the diagnostic approach. Unusual cutaneous presentation of these diseases has been found to be associated with development of immunity, virulent strain, drug resistance and immunosuppressive states. Also, because of globalization, climate change and large-scale migration, these manifestations have spread to new areas.
Summary:
Cutaneous manifestations of arthropod-borne infections are varied and nonspecific. Their atypical presentations are mainly related to immune impairment and strain virulence. When considering a patient with skin lesions, other clinical and laboratory features must be taken into account in order to make an accurate diagnostic approach.
Insights
Arthropod-borne diseases cause diverse skin lesions, including ulcers and nodules. Recognizing these varied cutaneous manifestations is crucial for diagnosis, especially with changing global factors.
Area of Science:
- Dermatology
- Infectious Diseases
- Public Health
Background:
- Arthropods are significant vectors for human skin infections, particularly in Latin America.
- Cutaneous manifestations are key indicators of arthropod-borne diseases, ranging from direct damage to systemic involvement.
Purpose of the Study:
- To review recent literature on the skin manifestations of arthropod-borne diseases.
- To emphasize diseases causing direct skin damage and those with systemic effects.
Main Methods:
- Systematic literature review of recent articles.
- Analysis of studies focusing on arthropod-borne diseases and their dermatological impact.
Main Results:
- Observed a variety and increase in cutaneous manifestations (petechiae, purpura, ulcers, nodules, etc.).
- Atypical presentations linked to immunity, strain virulence, drug resistance, and immunosuppression.
- Globalization and migration are expanding the geographic reach of these diseases.
Conclusions:
- Cutaneous signs of arthropod-borne infections are diverse and often nonspecific.
- Atypical presentations correlate with immune status and pathogen virulence.
- Accurate diagnosis requires integrating skin findings with clinical and laboratory data.
Related Concept Videos
Arboviral Encephalitis
Endocarditis II: Clinical Features of Infective Endocarditis
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Infectious Diseases and Their Occurrence
Hypersensitivity Reactions: Immune-Complex Reactions
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

