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Urinary phenolics and glucuronides in hexachlorocyclohexane isomers fed rats
K Srinivasan1, R Radhakrishnamurty
1Central Food Technological Research Institute, India.
Abstract:
Rats fed with dietary beta- and gamma-isomers of hexachlorocyclohexane excreted higher amounts of phenolics and glucuronides in the urine as compared to controls. The excretion profile of urinary phenolics and glucuronides suggested a relatively higher turnover rate of the gamma-isomer in the body as compared to the beta-isomer. Excretion of ethereal sulfate was low in hexachlorocyclohexane fed animals.