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Using ImageJ to evaluate optic disc pallor in traumatic optic neuropathy.

Sunah Kang1, Ungsoo Samuel Kim2

  • 1Department of Ophthalmology, Kim's Eye Hospital, Seoul, Korea.

Korean Journal of Ophthalmology : KJO
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Summary

ImageJ software effectively quantifies optic disc pallor in traumatic optic neuropathy (TON). This method shows a significant correlation with retinal nerve fiber layer (RNFL) thinning, aiding in diagnosis.

Keywords:
Fundus photographyOptic discOptic nerve injuriesOptical coherence tomography

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Neurology

Background:

  • Traumatic optic neuropathy (TON) is a severe condition affecting vision.
  • Assessing optic disc pallor is crucial for diagnosing and monitoring optic nerve damage.
  • Quantitative methods for evaluating disc pallor in TON are continuously being explored.

Purpose of the Study:

  • To evaluate the utility of ImageJ software for quantifying optic disc pallor in patients with traumatic optic neuropathy (TON).
  • To investigate the correlation between optic disc pallor and retinal nerve fiber layer (RNFL) thickness in TON.
  • To determine if ImageJ-based pallor assessment can serve as a reliable indicator of RNFL abnormalities.

Main Methods:

  • Unilateral TON patients were included in the study.
  • Optic disc photographs were analyzed using ImageJ software to quantify pallor in four quadrants.
  • Correlation analysis was performed between quantified optic disc pallor and optical coherence tomography (OCT) measured RNFL thickness.

Main Results:

  • A significant correlation was found between optic disc pallor and RNFL thickness across all quadrants (p < 0.05).
  • RNFL thinning was most frequently observed in the inferior quadrant.
  • The inferior quadrant showed the highest correspondence (39.3%) between disc pallor and RNFL thickness outside normative ranges.

Conclusions:

  • ImageJ software provides a reliable method for quantifying optic disc pallor in TON.
  • Quantified optic disc pallor significantly correlates with RNFL thickness abnormalities detected by OCT.
  • ImageJ-based assessment of disc pallor is a potentially valuable tool for evaluating RNFL thinning in TON.