Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Circuits01:25

Neural Circuits

3.0K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.0K
Action Potential01:14

Action Potential

10.2K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
10.2K
Neuronal Communication01:28

Neuronal Communication

5.5K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
5.5K
Understanding Interpersonal Attraction01:25

Understanding Interpersonal Attraction

627
Interpersonal attraction is a fundamental psychological phenomenon influencing human relationships across various contexts. It refers to one person's positive feelings or interests toward another, serving as the foundation for friendships, romantic partnerships, familial bonds, and professional relationships. The nature of interpersonal attraction extends beyond romantic connections, shaping interactions in both short-term and long-term social engagements.Psychological Foundations of...
627
Electrochemical Gradient and Channel Proteins: An Overview01:21

Electrochemical Gradient and Channel Proteins: An Overview

4.9K
An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell.  This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The blood-brain barrier-penetrating fusion protein BBB-ABP selectively binds amyloid-β oligomers and prevents in vitro neurotoxicity.

Journal of Alzheimer's disease : JAD·2026
Same author

Paradoxical inhibition of autonomic output following cortical suppression: When inhibiting an inhibitor results in more (not less) inhibition.

Neuropsychologia·2026
Same author

Intrinsic stabilization of synaptic plasticity improves learning and robustness in artificial neural networks.

Nature communications·2026
Same author

Time-delay reservoir for signal demixing using Kalman weight updates in fixed point and limit cycle regimes.

Scientific reports·2026
Same author

Phase gradient modulation of spiral waves in cortical circuits using the complex Ginzburg-Landau equation.

Journal of biological physics·2026
Same author

Neural heterogeneity enables adaptive encoding of time sequences.

Communications physics·2026

Related Experiment Video

Updated: May 1, 2026

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
09:47

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model

Published on: October 18, 2015

9.3K

Attractor dynamics in local neuronal networks.

Jean-Philippe Thivierge1, Rosa Comas1, André Longtin2

  • 1School of Psychology, University of Ottawa ON, Canada.

Frontiers in Neural Circuits
|April 2, 2014
PubMed
Summary
This summary is machine-generated.

Neural circuits with relay networks can synchronize but become inflexible. Selective gain inhibition enables flexible neural responses to stimuli, crucial for processing brief signals.

Keywords:
attractorcomputer simulationsmean fieldoscillationsspiking neuronssynchronization

More Related Videos

Fabrication of Magnetic Platforms for Micron-Scale Organization of Interconnected Neurons
09:54

Fabrication of Magnetic Platforms for Micron-Scale Organization of Interconnected Neurons

Published on: July 14, 2021

4.2K
External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

12.7K

Related Experiment Videos

Last Updated: May 1, 2026

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
09:47

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model

Published on: October 18, 2015

9.3K
Fabrication of Magnetic Platforms for Micron-Scale Organization of Interconnected Neurons
09:54

Fabrication of Magnetic Platforms for Micron-Scale Organization of Interconnected Neurons

Published on: July 14, 2021

4.2K
External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

12.7K

Area of Science:

  • Computational neuroscience
  • Systems neuroscience
  • Neural circuit dynamics

Background:

  • Synaptic motifs are fundamental to brain connectivity, linking small neuronal groups.
  • Relay network models propose that specific neuronal architectures can generate neural synchronization.

Purpose of the Study:

  • To investigate the impact of relay network architecture on neural circuit flexibility.
  • To identify mechanisms that enable adaptable neuronal responses to stimuli.

Main Methods:

  • Utilized two distinct computational models of neuronal dynamics.
  • Simulated neural circuits with a proposed relay network structure.
  • Implemented selective gain inhibition to modulate circuit activity.

Main Results:

  • Relay networks without inhibition led to a global attractor, hindering stimulus-modulated responses.
  • Selective gain inhibition successfully prevented fixed attractors, promoting flexible neural activity.
  • Simulated circuits demonstrated transient neural synchronization patterns.

Conclusions:

  • Fixed global attractors in relay networks limit neuronal response flexibility.
  • Selective gain inhibition is a viable mechanism for achieving adaptable neural processing.
  • Transient synchronization patterns may be essential for processing brief external stimuli.