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Updated: May 1, 2026

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
Published on: January 15, 2017
Did a quality improvement collaborative make stroke care better? A cluster randomized trial.
Maxine Power1, Pippa J Tyrrell, Anthony G Rudd
1Director of Innovation and Improvement Science, Salford Royal NHS Foundation Trust, Stott Lane, Salford, M6 8HD, England. maxine.power@nhs.net.
Quality improvement collaboratives (QICs) showed modest improvements in stroke care processes, but overall effectiveness remains uncertain. Further research is needed to optimize stroke care reliability and patient outcomes.
Area of Science:
- Neurology
- Public Health
- Healthcare Quality Improvement
Background:
- Stroke is a leading cause of death and disability.
- Variability in UK stroke care compliance is documented.
- The effectiveness of Quality Improvement Collaboratives (QICs) for stroke care reliability was previously unknown.
Purpose of the Study:
- To determine if a QIC, Stroke 90:10, could improve the reliability of stroke care processes.
- To compare compliance with care bundles in QIC-participating hospitals versus control hospitals.
Main Methods:
- A randomized controlled trial involving 24 NHS hospitals in Northwest England.
- Hospitals were assigned to either the Stroke 90:10 QIC (Breakthrough Series model) or a control group receiving standard care.
- Interrupted time series design and difference-in-difference analysis were used to assess changes in care bundle compliance.
Main Results:
- Hospitals in the QIC demonstrated modest improvements in compliance with the Early Hours Bundle (10.9% relative improvement) and the Rehabilitation Bundle (11.2% relative improvement).
- Data included 3,533 patients from intervention hospitals and 3,059 from control hospitals.
- Specific care processes showed varying sensitivity to the QIC intervention.
Conclusions:
- The QIC led to some improvements in stroke care but effects were modest.
- The overall impact of a Breakthrough Series QIC on stroke care quality requires further investigation.
- Certain aspects of stroke care may be more responsive to collaborative interventions than others.
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