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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
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Xantogranulomatous Pyelonephritis in children.
M Ubetagoyena1, M Fernandez Martin, L Gondra Sangroniz
1Seccion de Nefrologia Pediatrica y radiolofia Pediatrica. Hospital Universitario Donostia. San Sebastian.Spain.
Archivos Espanoles De Urologia
|April 3, 2014
Summary
Xanthogranulomatous Pyelonephritis (XP) is rare in children. Early diagnosis and treatment are crucial to prevent severe kidney damage in pediatric cases.
Area of Science:
- Pediatric Nephrology
- Urologic Pathology
Background:
- Xanthogranulomatous Pyelonephritis (XP) is a rare chronic inflammatory renal disease.
- It typically results from prolonged urinary tract obstruction and infection.
- XP is infrequently diagnosed in pediatric patients.
Observation:
- Two pediatric cases of XP are presented.
- One child presented with cloudy urine and hypergammaglobulinemia.
- The other was diagnosed during ultrasound for kidney stones, with inflammation extending to surrounding structures.
Findings:
- Both patients exhibited mild proteinuria and hematuria.
- Renal function and infection markers were normal in both cases.
- Surgical nephrectomy led to the resolution of all observed alterations.
Implications:
- This case series highlights uncommon presentations of XP in children.
- A high index of suspicion is necessary for timely diagnosis and management.
- Prompt treatment is vital to mitigate renal and extra-renal damage severity.
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