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Updated: May 1, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
Bioinformatics protocols in glycomics and glycoproteomics
Haixu Tang1, Anoop Mayampurath1, Chuan-Yih Yu1
1School of Informatics and Computing, Indiana University, Bloomington, Indiana.
Abstract:
Glycomics aims to identify the whole set of functional glycans of glycoconjugates (attached to proteins or lipids) in biological samples. Glycoproteomics aims to characterize the complete structure of all glycoproteins in biological samples, including the glycosylation sites of proteins and the various glycan structures attached to each of these sites. Mass spectrometry (MS) and microarray are high-throughput technologies that are commonly used in glycomics and glycoproteomics, which often result in the generation of large experimental datasets. Bioinformatics approaches play an essential role in automated analysis and interpretation of such data. This unit describes and discusses the computational tools currently available for these analyses, and their glycomics and glycoproteomics applications.
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