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Acute bronchiolitis in infants, a review
Knut Øymar1, Håvard Ove Skjerven, Ingvild Bruun Mikalsen
1Department of Paediatrics, Stavanger University Hospital, PO Box 8100, N-4068 Stavanger, Norway. knut.oymar@sus.no.
Insights
This article summarizes the epidemiology, pathophysiology, and diagnosis of acute viral bronchiolitis in infants. Key treatments include oxygen, fluid therapy, and minimal handling, with ventilation for severe cases.
Area of Science:
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background:
- Acute viral bronchiolitis is a frequent cause of infant emergency room visits.
- Physicians frequently encounter this condition in acutely ill children.
Purpose of the Study:
- To summarize the epidemiology, pathophysiology, and diagnosis of viral bronchiolitis in infants.
- To provide guidelines for the treatment of bronchiolitis in infants.
Main Methods:
- Review of current literature on viral bronchiolitis.
- Focus on established and emerging treatment strategies.
- Discussion of supportive care and respiratory support.
Main Results:
- Cornerstones of management include oxygen administration and fluid therapy.
- A "minimal handling approach" is recommended.
- Inhaled adrenaline has sparse evidence; hypertonic saline is an optional treatment.
Conclusions:
- Non-invasive and invasive ventilation may be necessary for respiratory failure.
- Treatment algorithms should be applicable across care levels and reflect local factors.
- Effective management requires a comprehensive approach to infant respiratory illness.
Abstract:
Acute viral bronchiolitis is one of the most common medical emergency situations in infancy, and physicians caring for acutely ill children will regularly be faced with this condition. In this article we present a summary of the epidemiology, pathophysiology and diagnosis, and focus on guidelines for the treatment of bronchiolitis in infants. The cornerstones of the management of viral bronchiolitis are the administration of oxygen and appropriate fluid therapy, and overall a "minimal handling approach" is recommended. Inhaled adrenaline is commonly used in some countries, but the evidences are sparse. Recently, inhalation with hypertonic saline has been suggested as an optional treatment. When medical treatment fails to stabilize the infants, non-invasive and invasive ventilation may be necessary to prevent and support respiratory failure. It is important that relevant treatment algorithms exist, applicable to all levels of the treatment chain and reflecting local considerations and circumstances.
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