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Related Experiment Video

Updated: May 1, 2026

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
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Short-term continuous-flow ventricular assist devices.

Hiroo Takayama1, Koji Takeda, Darshan Doshi

  • 1aDivision of Cardiothoracic Surgery bDivision of Cardiology, New York Presbyterian Hospital, Columbia University Medical Center, New York, New York, USA.

Current Opinion in Cardiology
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Summary

Short-term continuous-flow ventricular assist devices (CF-VADs) offer promising stabilization for patients with refractory cardiogenic shock (INTERMACS 1). Further research is needed to confirm their clinical efficacy.

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Area of Science:

  • Cardiology
  • Medical Devices
  • Mechanical Circulatory Support

Background:

  • Refractory cardiogenic shock, particularly in INTERMACS 1 patients, has a high mortality rate.
  • Innovations in continuous-flow pump technology have advanced both long-term and short-term ventricular assist devices.

Purpose of the Study:

  • To comprehensively update the current status of short-term continuous-flow ventricular assist devices (CF-VADs).
  • To review their application in treating refractory cardiogenic shock among INTERMACS 1 patients.

Main Methods:

  • Review of recent innovations in continuous-flow pump technology.
  • Analysis of the development and application of short-term CF-VADs (percutaneous and surgical).

Main Results:

  • Short-term CF-VADs demonstrate favorable features for temporary stabilization.
  • These devices serve as a crucial bridge-to-decision therapy for critically ill patients.
  • INTERMACS 1 patients with refractory cardiogenic shock show the worst outcomes.

Conclusions:

  • Current clinical evidence for short-term CF-VADs is based on small case series but appears promising.
  • Further rigorous clinical investigation is required to establish the overall efficacy of CF-VADs in refractory cardiogenic shock.