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Assessment of Lekhana Basti in the management of hyperlipidemia
Swapnil S Auti1, Anup B Thakar2, Vinay J Shukla3
1Ph.D. Scholar, Department of Panchakarma, Gujarat Ayurved University, Jamnagar, Gujarat, India.
Insights
Lekhana Basti significantly reduced cholesterol and LDL levels in hyperlipidemia patients. This Ayurvedic therapy also decreased body weight, BMI, and various body measurements, offering a holistic approach to managing metabolic disorders.
Area of Science:
- Ayurvedic Medicine
- Cardiovascular Health
- Metabolic Disorders
Background:
- Hyperlipidemia is a major risk factor for coronary heart disease and cerebrovascular disease, contributing significantly to global mortality.
- Characterized by elevated cholesterol levels, hyperlipidemia is linked to substantial cardiovascular and cerebrovascular disease burdens.
- In Ayurveda, hyperlipidemia can be understood within the concept of Medoroga, indicating a disorder of lipid metabolism.
Purpose of the Study:
- To evaluate the efficacy of Lekhana Basti in managing hyperlipidemia and associated metabolic parameters.
- To compare the effects of Lekhana Basti with a standard Ayurvedic treatment (Triphala Guggulu).
- To assess the impact of Lekhana Basti on objective measures of body composition and lipid profiles.
Main Methods:
- A randomized clinical trial involving 22 patients diagnosed with hyperlipidemia.
- Group A received Lekhana Basti, while Group B received Triphala Guggulu for 21 days.
- Measurements included serum cholesterol, LDL, apolipoprotein B, weight, BMI, body fat percentage, and various body circumferences and skinfold thicknesses.
Main Results:
- Lekhana Basti treatment resulted in a significant reduction in serum cholesterol (4.99%), LDL (9.13%), and apolipoprotein B (0.36%).
- Patients receiving Lekhana Basti showed significant decreases in weight, BMI, body fat percentage, and multiple body circumferences.
- The therapy also led to a reduction in skin fold thickness at various sites, indicating fat reduction.
Conclusions:
- Lekhana Basti demonstrates significant efficacy in reducing lipid parameters associated with hyperlipidemia.
- This Ayurvedic intervention is effective in improving objective parameters of body composition, suggesting a role in weight and fat management.
- Lekhana Basti offers a promising therapeutic option for managing Medodushti (metabolic dysfunction) and its related health risks.
Abstract:
Hyperlipidemia is highly prevalent and is closely related to coronary heart disease which is the most common cause of death. Raised cholesterol is estimated to be responsible for 18% of cerebrovascular disease and 56% of ischemic heart disease. Overall, these diseases account for about 4.4 million deaths (7.9% of the total). Based upon the etiological factors and symptom complexes, hyperlipidemia can be considered as a part of Medoroga. Being a Tikshna formulation, the treatment modality of Lekhana Basti is aimed basically for Apatarpana (emaciation) of the body, as Basti is the fastest Apatarpana. In the present clinical trial, a total of 22 patients were registered of whom 19 patients completed the course of the therapy. Under randomization, the registered patients were divided into two groups of which group A was treated with Lekhana Basti and group B was administered standard control drug, i.e., Triphala Guggulu, for 21 days. The results of the study revealed that in patients treated with Lekhana Basti, there was a decrease of about 4.99% in S. cholesterol, 9.13% in S. low density lipoprotein (LDL), and 0.36% in S. apolipoprotein B. Lekhana Basti was found to have significant effect in reducing the symptoms of Medodushti and in reduction of objective parameters like weight, body mass index (BMI), body fat percentage, body circumferences such as chest, abdomen, hip, pelvis, mid-thigh circumference, etc., and skin fold thickness as biceps, triceps, mid-arm, and abdominal skinfold thickness.
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