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Updated: May 1, 2026

Measuring Fluxes of Mineral Nutrients and Toxicants in Plants with Radioactive Tracers
Published on: August 22, 2014
Evaluation of intestinal transit time of root and leaves of Ipomea sepiaria
Sayani Majumder1, B K Ashok2, K Nishteswar3
1M. Pharma Scholar, Department of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
Abstract:
Ipomoea sepiaria Koenig Ex. Roxb is considered to be one of the source plants of the classical herb Lakshmana. In folklore, the herb is well known for its laxative activity. This plant belongs to Convolvulaceae family. It is observed that the plants of this family especially the species of Ipomoea are rich in purgative resins. The present experimental study was carried out to evaluate the effect of leaf and root of I. sepiaria on intestinal transit time on Swiss albino mice and the test drugs were administered in dose of 400 mg/kg. Evaluation of intestinal transit time was carried out by adopting Kaolin expulsion test and latency of onset of kaolin expulsion in fecal matter. The results shows that both root and leaf samples of I. sepiaria have marked intestinal motility enhancing property, among which leaf sample is found to be better. Hence, for the therapeutic purpose leaf can be preferred to get better activity profile and also to prevent destructive harvesting of the plant.
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