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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Intracranial Non-traumatic Aneurysms in Children and Adolescents
Angelika Sorteberg1, Daniel Dahlberg1
1Dept of Neurosurgery, Oslo University Hospital - Rikshsospitalet, The National Hospital, Oslo, Norway.
Insights
Pediatric intracranial aneurysms are rare but serious, differing from adult types. They often cause hemorrhage and require lifelong monitoring due to recurrence risks.
Area of Science:
- Pediatric Neurology
- Neurosurgery
- Vascular Neurology
Background:
- Pediatric intracranial aneurysms are rare but life-threatening vascular malformations.
- They present distinct pathophysiological characteristics compared to adult aneurysms.
- Limited case reports exist, highlighting the need for further research.
Purpose of the Study:
- To review the unique features of pediatric intracranial aneurysms.
- To discuss the clinical presentation, treatment challenges, and long-term outcomes.
- To emphasize the necessity of lifelong follow-up and screening.
Main Methods:
- Literature review of reported pediatric intracranial aneurysm cases.
- Analysis of epidemiological data, clinical manifestations, and treatment strategies.
- Comparison of pediatric versus adult aneurysm characteristics.
Main Results:
- Pediatric aneurysms show male predominance and higher symptomatic presentation rates with hemorrhage.
- Common sites include the internal carotid artery and posterior circulation; giant aneurysms are more frequent.
- Hemorrhage risk peaks around menarche in girls; re-hemorrhage rates are elevated.
- Mass effect symptoms and complex treatment needs are characteristic.
- Long-term outcomes are impacted by high recurrence and de novo aneurysm formation rates.
Conclusions:
- Pediatric intracranial aneurysms are a distinct entity requiring specialized management.
- Lifelong surveillance is crucial due to the high risk of aneurysm recurrence and new formation.
- Further research is needed to optimize long-term care and improve outcomes for affected children.
Abstract:
An intracranial aneurysm in a child or adolescent is a rare, but potentially devastating condition. As little as approximately 1200 cases are reported between 1939 and 2011, with many of the reports presenting diverting results. There is consensus, though, in that pediatric aneurysms represent a pathophysiological entity different from their adult counterparts. In children, there is a male predominance. About two-thirds of pediatric intracranial aneurysms become symptomatic with hemorrhage and the rate of re-hemorrhage is higher than in adults. The rate of hemorrhage from an intracranial aneurysm peaks in girls around menarche. The most common aneurysm site in children is the internal carotid artery, in particular at its terminal ending. Aneurysms in the posterior circulation are more common in children than adults. Children more often develop giant aneurysms, and may become symptomatic from the mass effect of the aneurysm (tumorlike symptoms). The more complex nature of pediatric aneurysms poses a larger challenge to treatment alongside with higher demands to the durability of treatment. Outcome and mortality are similar in children and adults, but long-term outcome in the pediatric population is influenced by the high rate of aneurysm recurrences and de novo formation of intracranial aneurysms. This urges the need for life-long follow-up and screening protocols.
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