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Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
Published on: February 17, 2022
Successful tocilizumab therapy in seven patients with refractory adult-onset Still's disease
Ei Bannai1, Hiroyuki Yamashita1, Shunta Kaneko1
1a Division of Rheumatic Diseases, National Center for Global Health and Medicine , Shinjuku-ku , Tokyo , Japan.
Abstract:
To evaluate the effects of tocilizumab (TCZ) on adult-onset Still's disease (AOSD), we reviewed medical records of seven patients with refractory AOSD treated with TCZ at our institution. TCZ therapy might allow rapid corticosteroid tapering and help maintain remission status, that is, resolution of clinical symptoms and normalization of biomarkers such as CRP and ferritin. Patients, however, should be monitored for the development of macrophage activation syndrome when TCZ is administered for active AOSD.
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