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Childhood insulinoma masquerading as seizure disorder

Kung-Ting Kao1, Peter J Simm, Justin Brown

  • 1Department of Paediatric Endocrinology and Diabetes, Monash Children's Hospital, Clayton, Australia.

Journal of Paediatrics and Child Health
|April 5, 2014
PubMed

Insights

This case highlights the critical need for blood glucose monitoring in children with new-onset seizures or behavioral changes. Prompt diagnosis of hyperinsulinaemic hypoglycaemia is crucial for effective management and surgical outcomes.

Area of Science:

  • Pediatric Endocrinology
  • Pediatric Neurology
  • Surgical Management of Endocrine Disorders

Background:

  • Hyperinsulinaemic hypoglycaemia is a rare but serious condition in children.
  • New-onset seizures and behavioral changes can be presenting symptoms.
  • Early diagnosis and management are vital to prevent long-term complications.

Observation:

  • A 9-year-old girl presented with seizures, weight gain, and early morning behavioral changes.
  • She was initially treated with anticonvulsants.
  • Diagnosis of hyperinsulinaemic hypoglycaemia was established subsequently.

Findings:

  • The case underscores the importance of blood glucose monitoring in pediatric patients with seizures or behavioral changes.
  • Challenges were encountered in lesion localization.
  • Achieving normoglycaemia before and after surgery proved difficult.

Implications:

  • Emphasizes the need for vigilant blood glucose monitoring in pediatric neurology.
  • Highlights diagnostic and therapeutic challenges in hyperinsulinaemic hypoglycaemia.
  • Informs clinical practice regarding the management of complex pediatric endocrine-metabolic disorders.

Keywords:
hypoglycaemiainsulinomapaediatricseizure

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