Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structural studies of human saliva.

P O Glantz1, J R Natiella, C D Vaughan

  • 1Department of Prosthetic Dentistry, Faculty of Odontology, University of Lund, Malmö, Sweden.

Acta Odontologica Scandinavica
|February 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New variable porosity flow diverter (VPOD) stent design for treatment of cerebrovascular aneurysms.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2012
Same author

Inositol, a constituent of thyroid gland effect on perfused rabbit's heart.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·2010
Same author

A protein-free fraction from desiccated thyroid substance of physiologic action.

Federation proceedings·2010
Same author

The difference in action of parasympathetic drugs in application to serosa or mucosa of the isolated intestine.

The American journal of physiology·2010
Same author

One year clinical performance and post-operative sensitivity of a bioactive dental luting cement--a prospective clinical study.

Swedish dental journal·2010
Same author

Panel discussion: section I.

Bulletin of the New York Academy of Medicine·2009
Same journal

Treatment preferences related to pulpectomy and prosthetic restorations among Lithuanian general dentists and prosthodontists.

Acta odontologica Scandinavica·2026
Same journal

Tissue response in hemisectioned primary mandibular second molars.

Acta odontologica Scandinavica·2026
Same journal

Exploring fulfillment of basic psychological needs in patients with dental anxiety: an investigation grounded in self-determination theory.

Acta odontologica Scandinavica·2026
Same journal

Relationship between dietary diversity and periodontitis: analysis of NHANES 2003-2014.

Acta odontologica Scandinavica·2026
Same journal

Associations between oral microbiome diversity and rheumatoid arthritis in U.S. adults: NHANES 2009-2012.

Acta odontologica Scandinavica·2026
Same journal

Complications of dermal filler treatments – a registry-based study from Finland.

Acta odontologica Scandinavica·2026
See all related articles

This study reveals novel microscopic structures in saliva, including a loose network and lipoid droplets. These findings offer new insights into saliva composition and oral microbiology.

Area of Science:

  • Oral biology
  • Microscopy
  • Salivary gland research

Background:

  • Saliva plays a crucial role in oral health, yet its detailed microscopic structure remains incompletely understood.
  • Previous studies have primarily focused on the biochemical composition of saliva, with less emphasis on its intricate structural organization at the cellular and molecular level.

Purpose of the Study:

  • To investigate the previously undescribed microscopic features of human saliva using advanced cryosectioning and staining techniques.
  • To characterize the structural organization of mixed saliva and specific salivary gland fractions (parotid, sublingual/submandibular).

Main Methods:

  • Human saliva samples (mixed, parotid, sublingual/submandibular) from four donors were rapidly frozen in liquid nitrogen.
  • Samples were sectioned using a microtome/cryostat and stained with various histological stains (hematoxylin-eosin, PAS, Alcian blue, Oil-red-O, Sudan Black B).

Related Experiment Videos

  • Stained sections were analyzed using light microscopy to identify structural components.

    • Main Results:

    • Previously undescribed features were observed in all saliva samples, including a loose overall network structure.
    • Collections of lipoid droplets, often loosely arranged, were a prominent finding.
    • Microorganism-like structures were frequently observed in mixed saliva, associated with epithelial cells and dense saliva components.

    Conclusions:

    • The developed cryosectioning and staining method effectively visualizes novel microscopic structures within human saliva.
    • The findings suggest a more complex structural organization of saliva than previously recognized, with implications for understanding oral physiology and pathology.
    • Further research is warranted to elucidate the functional significance of these newly identified salivary structures.