Related Experiment Video
Updated: May 1, 2026
09:32
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
6.6K
Atopic dermatitis in different skin types. What is to know?
1Department of Dermatology, Hospital Niño Jesús, Madrid, Spain.
Summary
Atopic dermatitis (AD) affects diverse global populations across all races and skin types. Environmental and genetic factors influence AD presentation, with higher prevalence noted in Black and mixed-race individuals.
Area of Science:
- Dermatology
- Genetics
- Epidemiology
Background:
- Atopic dermatitis (AD) is a global skin condition affecting diverse populations.
- Environmental and genetic factors significantly influence AD characteristics.
- Variations in AD prevalence and genetics exist across different racial and geographic groups.
Purpose of the Study:
- To review the global impact of atopic dermatitis (AD) across various populations.
- To examine the influence of race and genetics on AD presentation worldwide.
- To highlight differences in AD epidemiology and characteristics among diverse skin types.
Main Methods:
- Literature review of studies on atopic dermatitis.
- Analysis of epidemiological data concerning AD prevalence by race.
- Synthesis of research on genetic factors in AD across different ethnicities.
Main Results:
- Atopic dermatitis (AD) prevalence varies significantly among racial groups, appearing more common in Black and mixed-race populations.
- Distinct genetic backgrounds for AD have been identified in European, African, and Asian populations.
- Environmental influences further modulate AD presentation in different global communities.
Conclusions:
- Atopic dermatitis (AD) exhibits diverse clinical and genetic features globally.
- Understanding population-specific factors is crucial for effective AD management.
- Further research is needed to address health disparities in atopic dermatitis care.
Related Concept Videos
01:30Hypersensitivities
7.3K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
7.3K
01:23Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
01:27Acne Infection
94
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
94
01:21Accessory Structures of the Skin: Sebaceous Glands
5.5K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.5K
01:29Staphylococcal Skin Infections
143
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
143
01:27The Skin Microbiota
123
The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
123