Chemical profiling of Jinqi Jiangtang tablets by HPLC-ESI-Q-TOF/MS
Shi Sun1, Zhi-Shen Xie1, E-Hu Liu1
1State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Aim:
To profile the chemical constituents in Jinqi Jiangtang tablets.
Method:
Based on the chromatographic retention behavior, fragmentation patterns of chemical components, and published literatures, a high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (HPLC-ESI-Q-TOF/MS) method was established to characterize and identify components in Jinqi Jiangtang tablets.
Results:
A total of 52 chemical compounds, including eight iridoid glycosides, seven phenolic acids, twelve alkaloids, six flavonoids, and nineteen saponins, were identified in Jinqi Jiangtang tablets.
Conclusion:
The established method could serve as a powerful tool for structural characterization and quality control of this Chinese herbal preparation.
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