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Related Concept Videos

Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
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Longitudinal burn scar quantification.

Bernadette Nedelec1, José A Correa2, Ana de Oliveira3

  • 1School of Physical and Occupational Therapy, McGill University, Canada; Centre de recherche du Centre Hospitalier de l'Université de Montréal (CHUM), Canada; Hôpital de réadaptation Villa Medica, Canada.

Burns : Journal of the International Society for Burn Injuries
|April 8, 2014
PubMed
Summary

Quantitative analysis revealed that hypertrophic burn scars (HSc) remain thicker and less pliable than normal skin 12 months post-injury. Donor sites also show temporary redness, indicating incomplete recovery for burn scars.

Keywords:
BurnsCutometerHigh-frequency ultrasound scanningHypertrophic scarMexameterSkin injuries

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Area of Science:

  • Dermatology
  • Regenerative Medicine
  • Biomedical Engineering

Background:

  • Quantitative studies on burn scar recovery are limited.
  • Objective tools like ultrasound, Cutometer®, and Mexameter® can precisely measure scar characteristics.

Purpose of the Study:

  • To prospectively quantify the clinical recovery of hypertrophic scars (HSc), donor sites (D), and normal skin (N) over 12 months.
  • To compare scar thickness, pliability, erythema, and pigmentation using objective instruments.

Main Methods:

  • Prospective study involving 46 burn survivors.
  • Measurement of HSc, D, and N sites at 3, 6, and 12 months post-burn using high-frequency ultrasound, Cutometer®, and Mexameter®.
  • Mixed model regression analysis to compare means across sites and time points.

Main Results:

  • HSc thickness significantly decreased but remained greater than D and N skin at 12 months (p<0.0001).
  • Pliability improved in HSc and D sites but did not reach normal levels.
  • Erythema was higher in HSc and D sites at 3 and 6 months, with D sites nearing normal by 12 months.

Conclusions:

  • Post-burn HSc thickness, pliability, and erythema differ significantly from normal skin even at 12 months, showing improvement but not full recovery.
  • Donor sites exhibit temporary redness but tend to normalize by 12 months.
  • Color changes in scars are mainly due to erythema, not melanin, in this population.