Functional outcomes following total knee arthroplasty: a randomised trial comparing computer-assisted surgery with
William G Blakeney1, Riaz J K Khan2, Jennifer L Palmer1
1Department of Orthopaedic Surgery, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
The Knee
|April 8, 2014
Summary
Computer-assisted surgery (CAS) for total knee arthroplasty shows improved functional outcomes compared to conventional methods. Achieving neutral mechanical alignment is key for better patient results in knee replacement surgery.
Area of Science:
- Orthopedic Surgery
- Biomechanical Engineering
Background:
- Total knee arthroplasty (TKA) aims to restore function and alignment.
- Computer-assisted surgery (CAS) has demonstrated improved radiological alignment in TKA.
- Functional outcome data comparing CAS and conventional TKA methods remain limited.
Purpose of the Study:
- To compare functional outcomes between CAS and conventional surgical techniques for TKA.
- To evaluate the impact of surgical alignment on patient-reported functional scores.
Main Methods:
- A prospective study of 107 patients undergoing TKA by a single surgeon.
- Patients were randomized into three groups: CAS, intramedullary guides, and femur intramedullary/tibia extramedullary guides.
- Functional outcomes were assessed using the Short Form Health Survey (SF-12) and Oxford Knee Score (OKS).
Main Results:
- A trend towards higher OKS scores was observed in the CAS group at a median follow-up of 46 months.
- The OKS difference between CAS and conventional groups was statistically significant (p=0.024 unadjusted).
- Achieving a coronal mechanical axis within ±3° of neutral correlated with significantly better OKS (p=0.045).
Conclusions:
- Clinically significant differences in functional scores favor CAS over conventional guides at medium-term follow-up.
- A neutral coronal mechanical axis (within 3° of neutral) is associated with superior functional outcomes in TKA patients.


