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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Cancer Vaccines01:30

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Cancer02:18

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Related Experiment Video

Updated: May 1, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
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[Breast cancer screening].

Catherine Hill1

  • 1Institut Gustave-Roussy, 114, rue Edouard-Vaillant, 94805 Villejuif, France.

Presse Medicale (Paris, France : 1983)
|April 8, 2014
PubMed
Summary

Breast cancer screening offers a modest benefit, reducing mortality by 20-30%. However, overdiagnosis is minimal (under 10%), making screening more beneficial than detrimental for women

Area of Science:

  • Oncology
  • Public Health
  • Radiology

Context:

  • Ongoing debate surrounding the efficacy and risks of breast cancer screening.
  • Mammography is the primary screening tool, with benefits and harms requiring careful evaluation.

Purpose:

  • To quantify the mortality reduction attributable to breast cancer screening.
  • To estimate the rate of overdiagnosis in screened populations.

Summary:

  • Breast cancer screening demonstrates a mortality reduction of 20% in the invited population and 30% in the effectively screened population.
  • Accurate estimation of overdiagnosis is challenging; correctly adjusted figures indicate it affects less than 10% of screened women.
  • The overall benefit of breast cancer screening outweighs the detriments, though the net benefit is not substantial.

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Impact:

  • Provides evidence-based data to inform clinical guidelines and public health policies on breast cancer screening.
  • Aids women in making informed decisions about participating in breast cancer screening programs.
  • Highlights the importance of accurate statistical adjustment in evaluating screening program effectiveness.