Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Knockout in zebrafish suggests a role of BDNF in behavioural and cognitive plasticity.

Behavioral and brain functions : BBF·2026

Same author

A panel of medaka isogenic lines suggests individual, seasonal, and sexual genetic variation of <i>bdnf</i> gene expression in the brain.

Frontiers in behavioral neuroscience·2026

Same author

A potential role for BDNF in recognition behavior revealed through knockout in zebrafish.

Frontiers in behavioral neuroscience·2026

Same author

Cognitive individual differences are key in the network of trait covariance.

Behavioral ecology : official journal of the International Society for Behavioral Ecology·2026

Same author

Neurotoxic effects of binary and ternary fungicide mixtures in developing zebrafish: A multi-endpoint assessment.

Environmental toxicology and pharmacology·2026

Same author

Individual differences in inhibitory control may influence how endangered eels deal with river barriers during migration.

Animal cognition·2026

Same journal

Flexible Time-Series Analysis: A Dynamically Aware Method for Inferring Directed Dependencies in Behavioral Data.

Behavioural processes·2026

Same journal

Effects of group size and landmarks on escape behavior of three fish species.

Behavioural processes·2026

Same journal

Vocal individuality in two sympatric seabird species: The role of developmental strategy, analytical approach and sample size.

Behavioural processes·2026

Same journal

No evidence of sex-specific responses to chemosensory risk assessment cues in Harts rivulus.

Behavioural processes·2026

Same journal

Exploratory responses of rats to cage-mates and conspecifics from another cage in a habituation-dishabituation paradigm with multiple habituation stimuli.

Behavioural processes·2026

Same journal

Observation of drinking behaviour in the Ursus arctos marsicanus at a tree cavity (dendrotelm) in the central Apennines.

Behavioural processes·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 1, 2026

Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

Published on: July 12, 2021

Assessing memory in zebrafish using the one-trial test.

Tyrone Lucon-Xiccato¹, Marco Dadda¹

¹Dipartimento di Psicologia Generale, Università di Padova, Italy.

Behavioural Processes

|April 8, 2014

Summary

This summary is machine-generated.

Zebrafish can effectively use a simple one-trial memory test to assess memory function. This method allows for reliable memory assessment in fish without extensive training, similar to its use in mammals.

Keywords:

Fish Memory One-trial memory test

More Related Videos

The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

Published on: April 14, 2021

Behavioral Approaches to Studying Innate Stress in Zebrafish

Behavioral Approaches to Studying Innate Stress in Zebrafish

Published on: May 1, 2019

Related Experiment Videos

Last Updated: May 1, 2026

Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

Published on: July 12, 2021

The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

Published on: April 14, 2021

Behavioral Approaches to Studying Innate Stress in Zebrafish

Behavioral Approaches to Studying Innate Stress in Zebrafish

Published on: May 1, 2019

Area of Science:

Comparative cognition
Neuroscience
Animal behavior

Background:

Zebrafish are a valuable vertebrate model for studying memory.
The one-trial memory test is a reliable method for assessing memory in mammals.
This test bypasses the need for extensive training or rule learning.

Purpose of the Study:

To determine if a modified one-trial memory test is suitable for zebrafish.
To assess zebrafish memory function and impairment using a simplified protocol.

Main Methods:

Adult zebrafish were observed using a modified one-trial memory test.
Fish underwent a 25-minute familiarization phase with a novel object.
A test phase involved discriminating between the familiar object and a new object differing in shape and color.

Main Results:

Zebrafish demonstrated a clear tendency to explore novel objects.
Fish successfully memorized object characteristics.
Memory recall was evident irrespective of the 2, 6, or 24-hour delay between phases.

Conclusions:

The one-trial memory test is a suitable and simple method for assessing zebrafish memory.
This approach offers a reliable way to study memory function and impairment in fish.
Findings suggest broad applicability of this test across vertebrate models.