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LEOPARD syndrome: maxillofacial care.
Ikenna Valentine Aboh1, Glauco Chisci, Paolo Gennaro
1From the *Department of Maxillofacial Surgery, University of Siena, Siena; †Department of Maxillofacial Surgery, "Sapienza" University of Rome, Rome; and ‡Department of Pathology, University of Siena, Siena, Italy.
The Journal of Craniofacial Surgery
|April 8, 2014
Summary
This case report details a boy with LEOPARD syndrome experiencing rare mandibular osteolytic lesions and dental eruption issues. Management involved comprehensive diagnosis and maxillofacial care for facial swelling.
Area of Science:
- Dentistry
- Genetics
- Pathology
Background:
- LEOPARD syndrome is a rare genetic disorder.
- It is characterized by multiple lentigines, electrocardiographic abnormalities, ocular hypertelorism, facial abnormalities, genitourinary anomalies, retardation of growth and development, and deafness.
Observation:
- A pediatric patient presented with bilateral facial swelling.
- The patient was diagnosed with LEOPARD syndrome.
- Unusual mandibular osteolytic lesions and an eruption disorder were noted.
Findings:
- The mandibular lesions were osteoclastic-like, indicating bone destruction.
- The eruption disorder suggests compromised dental development.
- Systemic examinations confirmed the LEOPARD syndrome diagnosis.
Implications:
- This case highlights the dental and maxillofacial manifestations of LEOPARD syndrome.
- Early diagnosis and management are crucial for affected individuals.
- Further research into the specific oral pathology of LEOPARD syndrome is warranted.
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