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The normal transverse mesocolon and involvement of the mesocolon in acute pancreatitis: an MRI study

Xiao Xiao Chi1, Xiao Ming Zhang1, Tian Wu Chen1

  • 1Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, PR China.

Plos One
|April 8, 2014
PubMed
Abstract

Insights

Magnetic resonance imaging (MRI) can visualize transverse mesocolon involvement in acute pancreatitis (AP). The severity of this involvement correlates with AP severity, suggesting TMI as a useful supplementary indicator.

Area of Science:

  • Radiology
  • Gastroenterology
  • Medical Imaging

Background:

  • The transverse mesocolon's role in acute pancreatitis (AP) is not fully understood.
  • Standard imaging may not adequately assess mesocolonic changes in AP.

Purpose of the Study:

  • To characterize normal transverse mesocolon MRI findings.
  • To evaluate transverse mesocolon involvement (TMI) in AP using MRI.
  • To correlate TMI severity with AP severity using established scoring systems.

Main Methods:

  • Retrospective MRI analysis of 40 healthy controls and 210 AP patients.
  • Standardized grading of TMI severity (0-2 points).
  • Correlation analysis between TMI, MRI Severity Index (MRSI), and APACHE-II scores.

Main Results:

  • Normal transverse mesocolon anatomy visualized with high accuracy (95-100% for key vessels).
  • TMI detected in 61.9% of AP patients.
  • TMI severity showed strong correlations with MRSI (r=0.759) and APACHE-II (r=0.384) scores.

Conclusions:

  • MRI effectively visualizes transverse mesocolon abnormalities in AP.
  • TMI severity is a reliable indicator of AP severity.
  • TMI serves as a valuable supplementary imaging biomarker for AP severity assessment.

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