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Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR
15:16

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Published on: July 22, 2012

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Clinical characteristics and outcome in norovirus gastroenteritis

Min-Sho Ku1, Ji-Nan Sheu, Ching-Pin Lin

  • 1Department of Pediatrics, Chung Shan Medical University Hospital, No. 110 Jianguo North Road, Section 1, Taichung, 402, Taiwan.

Indian Journal of Pediatrics
|April 8, 2014
PubMed

Insights

Norovirus gastroenteritis in children presents distinct clinical features compared to bacterial infections, with prolonged vomiting and diarrhea. Early clinical signs can help identify norovirus in sporadic cases.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Microbiology

Background:

  • Acute gastroenteritis is a common illness in children.
  • Differentiating viral from bacterial causes is crucial for appropriate management.
  • Norovirus and rotavirus are significant viral pathogens in pediatric gastroenteritis.

Purpose of the Study:

  • To compare clinical characteristics of norovirus, rotavirus, and bacterial gastroenteritis in children.
  • To investigate outcomes of sporadic norovirus gastroenteritis.

Main Methods:

  • A cohort of 198 children (4 months to 14 years) with acute gastroenteritis was studied.
  • Clinical data, laboratory findings, and fecal specimens were analyzed.
  • Pathogens including norovirus, rotavirus, and bacteria were identified.

Main Results:

  • Norovirus infection was associated with significantly longer duration of vomiting and diarrhea, and fever compared to bacterial infections.
  • Clinical manifestations on the day after symptom onset were indicative of norovirus.
  • Hospital stay in norovirus patients correlated with diarrhea episodes and severity.

Conclusions:

  • Clinical presentation, particularly symptom duration and fever, can help identify norovirus gastroenteritis in children.
  • Early identification of norovirus is possible through clinical observation.
Abstract

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