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Updated: May 1, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Infection post-total knee replacement: current concepts
Pouya Alijanipour1, Javad Parvizi
1The Rothman Institute of Orthopaedics at Thomas Jefferson Hospital, 125 S 9th St, Ste 1000, Philadelphia, PA, 19107, USA, Pouya.alijanipour@rothmaninstitute.com.
Abstract:
Periprosthetic joint infection is a hot topic for investigation because it represents a challenging clinical problem with considerable burden for patients, institutions, and health systems. Despite our substantial knowledge, many details in prevention, pathophysiology, diagnosis, and treatment of infectious complications following total knee arthroplasty remain to be controversial with the available evidence being insufficient and at times conflictive. This manuscript is an attempt to approach the most recently published literature regarding the aforementioned details and aims to provide the reader with an updated perspective in the management of periprosthetic joint infection of the knee.
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