A dysmorphic newborn with petechiae and a 'Big Heart'
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Updated: May 1, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
Ling Zhi Bernice Oh1, Peng Mei Yvonne Ng, Thuan Chong Quah
1Department of Paediatrics, National University Hospital, Singapore, Singapore.
Abstract:
A male fetus was noted to have an isolated pericardial effusion. At birth, he had dysmorphic features of Down syndrome and extensive petechiae. He was diagnosed to have transient myeloproliferative disorder. The large pericardial effusion and TMD spontaneously resolved. At 4 years of age, he was diagnosed with acute megakaryoblastic leukaemia, underwent chemotherapy and achieved complete remission.
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