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5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
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Nephrogenic systemic fibrosis is associated with hypophosphataemia: a case-control study

Elana J Bernstein1, Tamara Isakova2, Mary E Sullivan2

  • 1Division of Rheumatology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, Division of Nephrology, Feinberg School of Medicine, Northwestern University, Chicago, IL, MGH Clinical Research Center, Massachusetts General Hospital, Boston, MA, Department of Neurology, Program for Neuropsychiatric Genomics, Brigham & Women's Hospital, Harvard Medical School, Boston, MA and Division of Rheumatology, Department of Medicine, University of Massachusetts Medical School and UMass Memorial Medical Center, Worcester, MA, USA. ejb2153@columbia.edu.

Rheumatology (Oxford, England)
|April 8, 2014
PubMed
Summary

Patients with stage 5 chronic kidney disease (CKD) and nephrogenic systemic fibrosis (NSF) exhibit lower phosphorus levels. This suggests phosphorus metabolism differences may contribute to NSF development beyond gadolinium-based contrast agent exposure.

Keywords:
chronic kidney diseasedialysisfibroblast growth factor 23gadoliniummagnetic resonance imagingnephrogenic systemic fibrosisphosphorus

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